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Gilbert Berdine, MD

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The Unfortunate Consequences of Biden's Vaccine Mandate

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The conflict over covid vaccines is coming to a climax. The Biden administration released its vaccine mandate. Enterprises with more than one hundred employees will be required to demonstrate that all employees either are fully vaccinated or both wear masks and are tested on a weekly basis. Texas has already challenged the constitutional basis for the mandate and the initial federal court ruling has blocked the mandate. The final court outcome of this case is uncertain.

The scientific basis for the mandate is dubious. We are told that the vaccine is effective and safe. If this assertion were true, there would be no reason for coercion, as everyone would voluntarily take the vaccine. Furthermore, anyone taking the vaccine would have nothing to fear from the unvaccinated. If the vaccine worked, then everyone taking the vaccine would be protected.

Of course, the vaccine does not work for everyone. Since the vaccine does not work for everyone, it becomes a judgment call whether the risk of vaccination is worth the benefit. Contrary to what is claimed on a daily basis, the vaccine is not safe. There is a Centers for Disease Control and Prevention database of adverse effects.


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How Much Does the Pfizer Vaccine Actually Reduce Risk of Hospitalization?

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The Food and Drug Administration (FDA) confirmed that the Pfizer covid vaccine is 95 percent effective, but what does that statement mean? The details of the Pfizer covid vaccine trial can be found here. As was the case in the previous announcement about the vaccine, this “efficacy” figure is misleading. The incidence of covid “cases” in the placebo group was 162 out of 18,325 subjects, or less than 1 percent. The incidence of “cases” in the vaccine group was 8 out of 18,198, or about one-twentieth the incidence of “cases” in the placebo group. The “efficacy” of 95 percent is an odds ratio between groups, but this ratio is comparing two uncommon or rare events. Although the benefit was statistically significant, the number to vaccinate in order to prevent a single “case” was 122, which is not nearly so impressive. For severe cases, the result was not statistically significant due to very small numbers (one severe case in the vaccine group and three severe cases in the control group). Even if these percentages persisted to statistical significance with larger numbers of subjects, the number to vaccinate in order to prevent a single severe case was over nine thousand, which is not impressive at all. There has been no statistically significant mortality benefit to date, and none of the deaths in either group (two in the vaccine group and four in the control group) were associated with covid-19.

Details of Trial

This was a double-blinded randomized control trial with 21,823 subjects in the vaccine group and another 21,828 subjects in the placebo group. Double-blind trials mean that neither the subjects nor the caregivers know whether subjects received vaccine or placebo. Randomized means that the subjects were put into the vaccine or placebo group by chance. The randomization is performed in a manner to balance the vaccine and placebo groups on the basis of significant characteristics such as age, race, and comorbid medical conditions. Subjects could not choose the group into which they would be enrolled.
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